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Founded by Claude Bernard in xix th century, experimental medicine oriented decisively medical research and especially modern biology. It is thanks to it that the role of the immune system, that is to say the means of defense developed by the organism against microbes, has been highlighted among other things.Located at the crossroads of genetics, immunology and pediatrics, Alain Fischer's work consists in identifying the genetic and molecular bases of rare diseases, hereditary immune deficiencies (IHL), causing infectious vulnerability, autoimmune diseases. ‐Inflammatory, autoimmune and sometimes cancer.

Medicine --- Health & Biological Sciences --- Medical Research --- recherche biomédicale --- système immunitaire --- médecine expérimentale --- immunologie

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When the end of life makes its inevitable appearance, people should be able to expect reliable, humane, and effective caregiving. Yet too many dying people suffer unnecessarily. While an "overtreated" dying is feared, untreated pain or emotional abandonment are equally frightening. Approaching Death reflects a wide-ranging effort to understand what we know about care at the end of life, what we have yet to learn, and what we know but do not adequately apply. It seeks to build understanding of what constitutes good care for the dying and offers recommendations to decisionmakers that address specific barriers to achieving good care. This volume offers a profile of when, where, and how Americans die. It examines the dimensions of caring at the end of life: * Determining diagnosis and prognosis and communicating these to patient and family. * Establishing clinical and personal goals. * Matching physical, psychological, spiritual, and practical care strategies to the patient's values and circumstances. Approaching Death considers the dying experience in hospitals, nursing homes, and other settings and the role of interdisciplinary teams and managed care. It offers perspectives on quality measurement and improvement, the role of practice guidelines, cost concerns, and legal issues such as assisted suicide. The book proposes how health professionals can become better prepared to care well for those who are dying and to understand that these are not patients for whom "nothing can be done."

Terminal care -- United States. --- Terminal care --- Social Control Policies --- Socioeconomic Factors --- Health Care Economics and Organizations --- Chemicals and Drugs --- Signs and Symptoms --- Life --- Suicide --- Sensation --- Investigative Techniques --- Hospitals, Special --- Psychology, Social --- Neurologic Manifestations --- Patient Care --- Health Care Quality, Access, and Evaluation --- Culture --- Diagnosis --- Patient Care Management --- Health Personnel --- Health Planning --- Community Health Services --- Motivation --- Sociology --- Persons --- Adult --- Morals --- Attitude --- Behavioral Symptoms --- Health Services Administration --- Patient Care Planning --- Biomedical Research --- Organizations --- Nursing Services --- Professional-Patient Relations --- Insurance, Health --- Information Science --- Health Services Accessibility --- Behavior --- Anthropology, Education, Sociology and Social Phenomena --- Financing, Organized --- Social Sciences --- Medical Assistance --- Legislation as Topic --- Jurisprudence --- Consumer Organizations --- Psychophysiology --- Residential Facilities --- Health Facilities --- Disclosure --- Research --- Health Care Facilities, Manpower, and Services --- Health Care --- Philosophy --- Ethics --- Behavior and Behavior Mechanisms --- Health Services --- Policy --- Nervous System Physiological Processes --- Social Problems --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Self-Injurious Behavior --- Therapeutics --- Named Groups --- Anthropology, Cultural --- Psychological Phenomena and Processes --- Population Characteristics --- Science --- Insurance --- Age Groups --- Public Assistance --- Occupational Groups --- Nervous System Diseases --- Comprehensive Health Care --- Pathological Conditions, Signs and Symptoms --- Interpersonal Relations --- Humanities --- Diseases --- Psychiatry and Psychology --- Natural Science Disciplines --- Anthropology --- Nervous System Physiological Phenomena --- Disciplines and Occupations --- Musculoskeletal and Neural Physiological Phenomena --- Phenomena and Processes --- Financing, Government --- Health Care Rationing --- Human Experimentation --- Palliative Care --- Public Policy --- Social Change --- Suicide, Assisted --- Consumer Participation --- Economics --- Health Services Research --- Pain --- Quality of Health Care --- Quality of Life --- Delivery of Health Care --- Hospitals --- Nursing Homes --- Social Control, Formal --- Social Values --- Terminally Ill --- Truth Disclosure --- Communication --- Home Care Services --- Physician-Patient Relations --- Self-Help Groups --- Family --- Medicaid --- Physicians --- Terminal Care --- Attitude to Death --- Hospices --- Social Responsibility --- Advance Directives --- Medicare --- Organizational Policy --- Stress, Psychological --- Aged --- Resource Allocation --- Cultural Diversity --- Pharmaceutical Preparations --- Prognosis --- Goals --- Patient Care Team --- Advance Care Planning --- Education --- Organization and Administration --- Medicine --- Health & Biological Sciences --- Terminal Care. --- End of Life Care --- Care End, Life --- Care Ends, Life --- Care, Terminal --- Life Care End --- Life Care Ends --- Death --- End-of-life care --- Terminally ill --- Care of the sick --- Critical care medicine --- Care and treatment --- Medical care --- levenseinde (einde van het leven, levenseindebeslissing) --- recht (wetgeving, rechtspraak, rechtsbeginselen, juridische aspecten, aansprakelijkheid) --- biomedisch, medisch-wetenschappelijk onderzoek --- ethiek (ethische aspecten) --- gezondheidszorg --- fin de vie (décision de fin de vie) --- droit (aspects juridiques, législation, jurisprudence, principes de droit, responsabilité) --- recherche biomédicale --- ethique (aspects ethiques) --- soins de santé --- Verenigde Staten --- Etats Unis --- levenseindezorg --- levenskwaliteit --- soins de fin de vie --- qualité de vie --- End-Of-Life Care --- Care, End-Of-Life --- End-Of-Life Cares